Epidermalgrowthfactorreceptor相关论文
Safety and efficacy of anti-EGFR monoclonal antibody (SCT200) as second-line therapy in advanced eso
Objective: The mainstay treatment of esophageal squamous cell carcinoma (ESCC) involves chemotherapy and immunotherapy. ......
Background::Previous studies have shown that bufalin exerts antitumor effects through various mechanisms. This study aim......
Stattic sensitizes osteosarcoma cells to epidermal growth factor receptor inhibitors via blocking th
Osteosarcoma (OS),the most common malignant bone tumor with high metastatic potential,frequently affects children and ad......
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目的:探讨表皮生长因子受体（EGFR）基因不同突变状态非小细胞肺癌（NSCLC）患者临床特征及疗效的差异。方法:回顾性分析2018年4月至2020年......
Cyclooxygenase-2 expression is dependent upon epidermal growth factor receptor expression or activat
Aim: To investigate the expression of cyclooxygenase-2 (COX-2) and epidermal growth factor receptor (EGFR) and the possi......
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Trefoil factors: Tumor progression markers and mitogens via EGFR/MAPK activation in cholangiocarcino
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Concurrent TP53 mutations predict poor outcomes of EGFR-TKI Treatments in Chinese patients with adva
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the predictive value of of radiologic features of ground-glass opacity on tumor invasiveness and epi
Objectives Evaluation of ground-glass opacity (GGO) is a longstanding clinical problem.We aimed to investigate the compu......
Intracavitary chemotherapy with EGFR-TKI is not superior to TKI monotherapy in controlling malignant
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MUC3A induces PD-L1 and reduces tyrosine kinase inhibitor effects in EGFR-mutant non-small cell lung
Objective Lung cancer is one of the leading causes of cancer-related mortality in the world,and non-small cell lung canc......
Plumbagin Ameliorates CCl4-induced Hepatic Fibrosis in Rats via the Epidermal Growth Factor Receptor
Objective Epidermal growth factor(EGF)and its signaling molecules — EGFreceptor(EGFR)and signal transducer and activato......
EGFR-targeting antibodies enhance the irradiation response of esophageal cancer cell lines of differ
There is an established relationship between epidermal growth factor receptor (EGFR) expression and tumor cell prolifera......
Blockade of methylation enhances the therapeutic effect of gefitinib in non-small cell lung cancer c
Background: The sensitivity of lung cancer to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) ha......
Dexmedetomidine, a sedative/anesthetic and neuroprotective drug, acts via astrocytic α2-adrenergic r
Dexmedetomidine, a sedative/anesthetic drug is associated with a lower incidence of delirium and reduced length of venti......
Scutellariabarbata D.Doninhibits non-small cell lung cancer growth via and targeted regulation of EG
Scutellariabarbata D.Don (SB) is commonly used to treat lung cancer in Chinese medicine but the underlining mechanism is......
Aim:Erlotinib is used to treat non-small-cell lung cancer (NSCLC), which targets epidermal growth factor receptor (EGFR)......
Combination therapy with VEGFR2 and EGFR siRNA enhanced the antitumor effect of cisplatin in non-sma
siRNA targeting the murine VEGFR2 gene was designed and validated for efficient and robust silencing in vitro, and was t......
Antitumor activity of EGFR-specific CAR-T cells against non-small-cell lung cancer cells in vitro an
Objectives:Effective controls of non-small lung cancer(NSCLC) are still a clinical challenge,especially advanced stages ......
Structure-based design and synthesis of L858R/T790M selective epidermal growth factor receptor inhib
Mutated epidermal growth factor receptor(EGFR)is a major driver of non-small cell lung cancer(NSCLC)....
Design, Synthesis and Biological Evaluation of 4-aniline Quinazoline Derivatives as Novel EGFR Inhib
Epidermal growth factor receptor (EGFR) belongs to the ErbB family of receptor tyrosine kinases which play indispensable......
Serum microRNA expression profiling revealing potential diagnostic biomarkers for lung adenocarcinom
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Epidermal growth factor receptor stabilizes programmed death ligand 1 by glycosylation in colorectal
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Risk factors and treatments for brain metastasis in patients with adenocarcinoma of the lung: a retr
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Diagnostic Values of Vascular Endothelial Growth Factor and Epidermal Growth Factor Receptor for Ben
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Objective:Bufalin is an effective drug for the treatment of liver cancer.But its high toxicity,poor water-solubility,fas......
Discovery of pteridin-7(8H)-one-based Irreversible Inhibitors targeting Epidermal Growth Factor Rece
The EGFR T790M variant is an important mutation resulting in approximately 50％ of the clinically acquired resistance to a......
Combination of Oridonin and Cetuximab Synergistically Exerts Apoptosis and G2M Arrest on Laryngeal S
Epidermal growth factor receptor(EGFR),a transmembrane glycoprotein,is expressed at high levels in a large proportio......
Objective: To investigate thecorrelation between the EGFR expression profile, FGFR gene mutation and clinicopatholog......
表皮生长因子受体（epidermal growth factor receptor，EGFR）通路异常在肿瘤发生、发展过程中起到非常重要的作用，特异性抑制该通路的小......
Objective:To study the expressions and clinical significances of PCNA, EGFR, Bcl-2 and Bax in thymoma. Methods: The expr......
目的对晚期非小细胞肺癌合并恶性胸腔积液患者的胸腔积液表皮生长因子受体(EGFR)突变情况进行研究，总结其临床意义，为个体化的临床治......
目的研究表皮生长因子受体(EGFR)抑制剂C225对宫内感染仔鼠脑组织炎症的影响。方法应用脂多糖(LPS)感染孕鼠建立宫内感染孕鼠模型,......
锌元素能够以自由离子的形式在细胞内作为一种信号分子，通过对多个关键环节的影响，从而对细胞信号转导起到重要的调控作用。这些环节......
在全球范围内，肿瘤的致死率仍然居高不下，如何加强肿瘤治疗及改善患者的生存质量仍是目前关注的焦点和亟需解决的问题。分子靶向治疗......
肺癌是目前全球癌症患者中病死率最高的，其中，非小细胞肺癌（ NSCLC ）的研究覆盖最广。目前，人类表皮生长因子受体（ EGFR）研究的兴起，使EGFR......
卵巢癌起病隐匿、缺乏早期诊断手段、预后不良，严重威胁女性健康。而传统的手术及化疗治疗远期疗效不理想。近年来，与卵巢癌相关的信......
Impact of high-fat diet and vitamin D3 supplementation on aortic stenosis establishment in waved-2 e
Objective:The use of animal models of aortic stenosis (AS) remains essential to further elucidate its pathophysiology an......
目的：探讨EGFR在人胃癌中的表达及其与预后的相关性。方法选择2008年7月至2011年5月河南大学第一附属医院收治的有随访结果且资料完......
